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RADIL

The RADIL professional staff has operated a laboratory animal diagnostic laboratory for over 40 years. Our professional staff includes a wide breadth of expertise including ACLAM-boarded veterinarians and PhD microbiologists, molecular biologists, geneticists and cryobiologists. 

RADIL will be closed Thursday, November 26 in observance of Thanksgiving Day.  Please plan your shipments accordingly.



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Cell Lines and Tumors Harboring Human Pathogens
November 19th, 2009

Cell lines and tumors obtained from human patients are important tools for biomedical research.  However, biological materials may harbor human pathogens that are potentially infectious and transmissible.  In many cases, human cell lines and tumors are used in research without assessing their pathogen status, which poses a potential health hazard to researchers handling these materials. 

Of approximately 800 cell lines and tumors tested at RADIL, 0.61% of specimens were positive for HIV and 0.49% were positive for Hepatitis B.  These data highlight the importance of testing human biological materials that are used in laboratory settings. 

As of December 1, 2009, RADIL clients may choose from h-IMPACT I, a comprehensive Human pathogen profile, or h-IMPACT II, a profile which tests for only the most prevalent of human pathogens.

For more information regarding the new RADIL h-IMPACT profiles, please see the PCR section of this website.

What pathogen do the RADIL diagnostic labs see most often in rats?

By an overwhelming margin, the most prevalent pathogen that we see in rats is RTV/TMEV (or Rat Theiler Virus).  Also known as Rat Theilovirus, TMEV-like virus of rats, and Rat encephalomyelitis virus, RTV is present two to two and a half times more frequently than RCV, RMV, PVM or H-1.  RADIL has both an MFI serologic assay as well as a PCR assay with which to test for RTV. 

For more detailed information about RTV prevalence, download RTV Prevalency Data excerpted from Infectious Agents in Laboratory Rodents.

Read More! Submit a question to the RADIL Staff
RADIL Introduces Pinworm by PCR Testing
November 19th, 2009

In the past, in order to accurately determine the presence of pinworms in an animal has required a post-mortem direct exam.  With the introduction of RADIL's new PCR assay which tests for both Syphacia obvelata and Aspiculuris tetraptera, antemortem testing can now be performed with highly accurate results.  RADIL's Pinworm PCR assay is nearly as sensitive as the direct exam and has the advantage that the animal does not need to be euthanized for evaluation.  In studies, it was also more sensitive than either of the two antemortem tests (tape test and fecal float).

Pinworm by PCR evaluation will be available beginning December 1, 2009 as part of the Mouse Basic , Mouse Comprehensive and Rat Basic Fecal Panels, as a Helicobacter & Pinworm panel, or as a stand-alone assay.  For more information and pricing, please click here. 

( for more info click here )
MFI2 - The next generation in serology testing
November 19th, 2009

At this year's National AALAS Meeting in Denver, Colorado, RADIL introduced a breakthrough serologic testing technology that will offer clients an increased level of results confidence for the most prevalent mouse and rat agents.  MFI2 represents an advanced approach to serologic monitoring for laboratory animal pathogens, providing the highest level of diagnostic accuracy available.   By evaluating multiple antigens for each agent, primary and confirmatory testing now occur at the same time, saving time and increasing the predictive value of the final results.  Clients will begin seeing multiple antigens reported on case reports as of December 1, 2009.

For more information regarding MFI2, please visit the Serology section of this site.

( for more info click here )
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