BIOLOGICAL MATERIALS TESTING
RADIL has developed and validated a PCR-based alternative to MAP testing. Contamination of biological specimens, such as cell lines, hybridomas and tumor cells, with rodent pathogens can result in devastating outbreaks of disease in laboratory animals implanted with these materials and confounding and deleterious effects on tissue culture-based experiments. The traditional method for testing biological specimens for murine pathogens has been the Mouse Antibody Production (MAP) test. The major disadvantage of MAP testing is the 6 to 8 weeks required to get results. To address this issue, our laboratory has developed the Infectious Microbe PCR AmplifiCation Test or IMPACT , which is a panel of PCR assays that detects murine pathogens. Comparison of IMPACT results with MAP testing results for representative DNA and RNA viruses indicated that the sensitivity of the IMPACT was equal or greater than that of MAP testing. Turnaround time for IMPACT results is 5 business days. The cost of testing by the IMPACT is markedly lower than commercial MAP testing.
IMPACT Profiles - MiceIMPACT Profiles - Rats
IMPACT Profile - Hamsters
IMPACT Profile - Comphrehensive Murine Panel
IMPACT Profiles - Mice
|
IMPACT Profile I
(22 Agent Tests) $456.50* |
IMPACT Profile II
(19 Agent Tests) $394.40* |
IMPACT Profile III
(16 Agent Tests) $358.25* |
IMPACT Profile IV
(9 Agent Tests) $185.50* |
|---|---|---|---|
| Mycoplasma spp. | Mycoplasma spp. | Mycoplasma spp. | Mycoplasma spp. |
| Sendai virus | Sendai virus | Sendai virus | Sendai virus |
| Mouse hepatitis virus | Mouse hepatitis virus | Mouse hepatitis virus | Mouse hepatitis virus |
| Pneumonia virus of mice | Pneumonia virus of mice | Pneumonia virus of mice | Pneumonia virus of mice |
| Minute virus of mice | Minute virus of mice | Minute virus of mice | Minute virus of mice |
| Mouse parvovirus (MPV1, MPV2, MPV3) | Mouse parvovirus (MPV1, MPV2, MPV3) | Mouse parvovirus (MPV1, MPV2, MPV3) | Mouse parvovirus (MPV1, MPV2, MPV3) |
| Theiler's murine encephalomyelitis virus | Theiler's murine encephalomyelitis virus | Theiler's murine encephalomyelitis virus | Theiler's murine encephalomyelitis virus |
| Murine norovirus | Murine norovirus | Murine norovirus | |
| Reovirus 3 | Reovirus 3 | Reovirus 3 | |
| Mouse rotavirus | Mouse rotavirus | Mouse rotavirus | |
| Ectromelia virus | Ectromelia virus | Ectromelia virus | |
| Lymphocytic choriomeningitis virus | Lymphocytic choriomeningitis virus | Lymphocytic choriomeningitis virus | |
| Polyoma virus | Polyoma virus | Polyoma virus | |
| Lactate dehydrogenase-elevating virus | Lactate dehydrogenase-elevating virus | Lactate dehydrogenase-elevating virus | |
| Mouse adenovirus (MAD1, MAD2) | Mouse adenovirus (MAD1, MAD2) | ||
| Mouse cytomegalovirus | Mouse cytomegalovirus | ||
| K virus | |||
| Mouse thymic virus | |||
| Hantaan virus |
* A 5% discount is applied to each case with 5 or more samples.
A 10% discount is applied to each case wtih 10 or more samples.
IMPACT Profiles - Rats
|
IMPACT Profile V
(15 Agent Tests) $381.00* |
IMPACT Profile VI
(11 Agent Tests) $298.70* |
|---|---|
| Mycoplasma spp. | Mycoplasma spp. |
| Pneumonia virus of mice | Pneumonia virus of mice |
| Kilham's rat virus | Kilham's rat virus |
| Toolan's H1 virus | Toolan's H1 virus |
| Rat parvovirus | Rat parvovirus |
| Lymphocytic choriomeningitis virus | Lymphocytic choriomeningitis virus |
| Rat cytomegalovirus | Rat cytomegalovirus |
| Sendai virus | Sendai virus |
| Rat coronavirus | Rat coronavirus |
| Sialodacryoadenitis virus | Sialodacryoadenitis virus |
| Rat minute virus | Rat minute virus |
| Seoul virus | |
| Mouse adenovirus | |
| Reovirus 3 | |
| Theiler's murine encephalomyelitis like virus |
* A 5% discount is applied to each case with 5 or more samples.
A 10% discount is applied to each case wtih 10 or more samples.
IMPACT Profile – Hamsters
|
IMPACT Profile VII
(11 Agent Tests) $298.70* |
|---|
| Mycoplasma spp. |
| Pneumonia virus of mice |
| Kilham's rat virus |
| Toolan's H1 virus |
| Hamster parvovirus |
| Lymphocytic chorlomeningtis virus |
| Minute virus of mice |
| Theiler's murine encephalomyelitis virus |
| Sendai virus |
| Reovirus 3 |
| Hantaan virus |
* A 5% discount is applied to each case with 5 or more samples.
A 10% discount is applied to each case wtih 10 or more samples.
IMPACT Profile – Comprehensive Murine Panel
|
IMPACT Profile VIII
(31 Agent Tests) $659.00* |
|---|
| Mycoplasma spp. |
| Sendai |
| Mouse hepatitis virus |
| Pneumonia virus of mice |
| Minute virus of mice |
| Mouse parvovirus (MPV1, MPV2, MPV3) |
| Reovirus 3 |
| Mouse rotavirus |
| Ectromelia virus |
| Lymphocytic choriomeningitis virus |
| Polyoma virus |
| K virus |
| Mouse adenovirus (MAD1, MAD2) |
| Mouse cytomegalovirus |
| Lactate dehydrogenase-elevating virus |
| Mouse thymic virus |
| Hantaan virus |
| Kilham’s rat virus |
| Toolan’s H1 virus |
| Rat parvovirus |
| Rat cytomegalovirus |
| Rat coronavirus |
| Rat minute virus |
| Sialodacryoadenitis virus |
| Seoul virus |
| Theiler’s murine encephalomyelitis virus |
| Theiler’s murine encephalomyelitis like virus |
* A 5% discount is applied to each case with 5 or more samples.
A 10% discount is applied to each case wtih 10 or more samples.
h-IMPACT Profile
h-IMPACT results provided for research purposes only
|
h-IMPACT Profile
(9 Agent Tests) $231.75* |
|---|
| Human immunodeficiency virus (HIV1, HIV2) |
| Hepatitis viruses (A, B and C) |
| Hantaviruses (Hantaan, Seoul, Sin Nombre) |
| Mycoplamsa spp. |
* A 5% discount is applied to each case with 5 or more samples.
A 10% discount is applied to each case wtih 10 or more samples.